Movement Disorders (revue)

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The subthalamic nucleus, oscillations, and conflict.

Identifieur interne : 000030 ( Main/Exploration ); précédent : 000029; suivant : 000031

The subthalamic nucleus, oscillations, and conflict.

Auteurs : Baltazar Zavala [États-Unis] ; Kareem Zaghloul ; Peter Brown

Source :

RBID : pubmed:25688872

Abstract

The subthalamic nucleus (STN), which is currently the most common target for deep brain stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the past few years for the roles it may play in functions beyond simple motor control. In this article, we highlight several of the theoretical, interventional, and electrophysiological studies that have implicated the STN in response inhibition. Most influential among this evidence has been the reported effect of STN DBS in increasing impulsive responses in the laboratory setting. Yet, how this relates to pathological impulsivity in patients' everyday lives remains uncertain.

DOI: 10.1002/mds.26072
PubMed: 25688872


Affiliations:


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